Al-Ishtus rules over the domain of Poison, and is commonly known as the God of the Deserts. This is due to the fact that the majority of his worshipers come from desert-wandering tribes.
According to legend, Al-Ishtus claimed godhood through cleverness and blackmail. He grew up as a part of a nomadic clan in a desert, specializing in the creation of poisons and antidotes, typically using snake or scorpion venom. He supposedly crafted a poison that could kill gods through their followers, by following the trails of divine energies that the gods used to grant mortals power. Out of fear (and a bit of admiration), Boccob and the other deities agreed to raise him to the Pantheon, in exchange for this poison to never see the light of day.
Al-Ishtus’ followers are mostly gathered in desert regions. Those that are not tend to have professions relating to the usage of poison, either in its use (such as an assassin), or those who attempt to prevent poison by crafting antidotes. His holy symbol is a scorpion, typically inside an inverted triangle.